Nolvadex

VGL Fitness Tamoxifen Citrate 20mg, a trusted SERM for post-cycle therapy and oestrogen control. Nolvadex 20mg is essential for maintaining gains, supporting natural testosterone recovery, and reducing the risk of gyno during or after cycles.

Nolvadex – Harm Reduction Crib Sheet

Compound: Tamoxifen Citrate (Nolvadex)
Class: Selective Oestrogen Receptor Modulator (SERM)
Administration: Oral

Dosage

• PCT Protocol:
  • 40 mg/day (Weeks 1–2)
  • 20 mg/day (Weeks 3–4)
• On-Cycle Gynecomastia Management: 10–20 mg/day (only if symptoms appear)
• Clinical Use: 20–40 mg/day for breast cancer and hormonal regulation

Half-Life

• ~5 to 7 days
• Active metabolites extend functional activity; once-daily dosing sufficient

Benefits

• Blocks oestrogen receptors in breast tissue → prevents or treats gynecomastia
• Stimulates LH and FSH → promotes natural testosterone production
• Essential component of most post-cycle therapy (PCT) protocols
• May help restore HPTA function after AAS use

Side Effects

• Hot flashes
• Nausea
• Mood swings or irritability
• Visual disturbances (rare)
• Possible mild clotting risk (rare in healthy males)
• Libido suppression in some users (temporary)

Risks

• Thromboembolic risk: Increased clotting risk in predisposed individuals (rare in young, healthy males)
• Visual changes: Blurred vision or floaters (rare, dose-dependent)
• Liver metabolism: Hepatic enzyme elevation possible at high doses or long duration
• Not suitable for women: Risk of hormonal imbalance or menstrual disruption

Risk Mitigation

• Bloodwork: Check LH, FSH, TT/FT pre- and post-PCT
• Avoid long-term use: Limit to 4–6 weeks unless medically directed
• Monitor for side effects: Especially vision or mood-related
• Combine with Clomiphene (optional): In highly suppressive cycles for synergistic effect
• Do not use as standalone anti-oestrogen during cycle unless required – AI preferred for prevention

Use Cases in Bodybuilding

• Post-Cycle Therapy (PCT): Primary use; restores natural testosterone production
• On-Cycle Emergency: For gynecomastia flare-ups if no AI is available
• Bridging: Sometimes used between cycles to maintain HPTA activity (limited efficacy)
• Test base support: Useful in cycles where oestrogen control is required but AIs are not tolerated